Sleep disorder associated with antibodies to IgLON5: parasomnia or agrypnia?
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چکیده
منابع مشابه
Sleep disorder associated with antibodies to IgLON5: parasomnia or agrypnia?-Authors' reply.
We read with great interest the paper by Lidia Sabater and colleagues, who describe a novel neuroimmuno logical disease that is a complex, severe sleep disorder associated with antibodies to IgLON5. We have noted a clinically similar disorder in a single patient who had serum and CSF antibodies to the metabotropic GABAB receptor. Similar to the patients in Sabater and colleagues’ report, our pa...
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Lidia Sabater, PhD1,*, Carles Gaig, MD1,2,3,*, Ellen Gelpi, MD1,4,*, Luis Bataller, MD5,7, Jan Lewerenz, MD6, Estefanía Torres-Vega, BSc7, Angeles Contreras, MD8, Bruno Giometto, MD9, Yaroslau Compta, MD2, Cristina Embid, MD3,10, Isabel Vilaseca, MD3,11, Alex Iranzo, MD1,2,3, Joan Santamaría, MD1,2,3, Josep Dalmau, MD1,12,13, and Francesc Graus, MD1,2 1Institut d'Investigacions Biomèdiques Augu...
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OBJECTIVE To report on dysphagia as initial sign in a case of anti-IgLON5 syndrome and provide an overview of the current literature. METHODS The diagnostic workup included cerebral MRI, fiber optic endoscopic evaluation of swallowing (FEES) with the FEES tensilon test, a videofluoroscopic swallowing study, evoked potentials and peripheral nerve conduction studies, polysomnography, lumbar pun...
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A novel syndrome characterized by a distinctive sleep disorder accompanied by variable symptoms of brainstem involvement and a highly restricted haplotype was recently described in association with antibodies to a neuronal cell adhesion protein named IgLON5. Because of the symptoms and chronic disease progression, most of these patients are primarily seen by specialists in sleep and neurodegene...
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ورودعنوان ژورنال:
- The Lancet. Neurology
دوره 13 9 شماره
صفحات -
تاریخ انتشار 2014